Hindu Editorial Analysis : 16-August-2023

Air pollution, a critical issue affecting global health, has been found to have far-reaching consequences beyond respiratory problems. A recent analysis published in The Lancet Planetary Journal highlights a concerning relationship between particulate matter and antimicrobial resistance (AMR). Particulate matter, specifically PM2.5, has been identified as a potential carrier for antibiotic-resistant bacteria and genes, paving the way for a new dimension of public health risks.

Understanding Particulate Matter & Antimicrobial Resistance

Particulate matter, or PM, refers to tiny particles suspended in the air, with PM2.5 being particles smaller than 2.5 micrometers in diameter. These minuscule particles, when laden with unhealthy levels of PM2.5, could be contributing to a surge in antimicrobial resistance. AMR occurs when disease-causing bacteria evolve to resist the drugs that were once effective in combating them. This phenomenon poses a significant threat to public health, as it renders infections harder to treat and can lead to severe illness and even death.

Global Impact and Economic Consequences

The consequences of this airborne transmission of antibiotic-resistant bacteria and genes have been profound, particularly in densely populated countries like India and China. The Lancet study estimates that in 2018, this phenomenon could have led to the premature loss of 18.2 million years of life worldwide. The economic toll is staggering, amounting to a loss of $395 billion, surpassing the GDP of countries like Pakistan.

The Connection: PM2.5 and AMR

The researchers discovered a notable correlation between air pollution and antimicrobial resistance. For every 10% rise in air pollution, there was a corresponding 1.1% increase in AMR across different countries and regions. PM2.5 emissions from sources such as burning firewood for cooking or heating were identified as carriers of bacteria and antibiotic-resistant genes. These particles can travel over long distances, eventually being inhaled by individuals. PM2.5 particles can penetrate the body’s defenses, entering the bloodstream and lungs, thereby exacerbating chronic conditions like cancer, heart disease, and asthma.

Antimicrobial Resistance in India

India emerges as a focal point in the fight against AMR due to its high antibiotic usage, both among humans and animals. Factors such as indiscriminate antibiotic use, poor hygiene, and inadequate sanitation practices have fueled this trend. The COVID-19 pandemic worsened the situation, leading to increased antibiotic sales for treating respiratory infections. The widespread presence of antibiotic-resistant bacteria in India’s rivers and lakes further intensifies the challenge.

Root Causes and Drivers of AMR

The root causes of antimicrobial resistance are multifaceted, including the overuse and misuse of antibiotics. This escalating problem stems from various factors:

  • Inadequate WASH Facilities: Lack of access to clean water, sanitation, and hygiene for both humans and animals.
  • Healthcare and Farm Practices: Poor infection and disease prevention in healthcare settings and farms.
  • Limited Access to Medicines: Inadequate access to quality, affordable medicines, vaccines, and diagnostics.
  • Lack of Awareness: Insufficient public awareness and knowledge about responsible antibiotic use.
Consequences of AMR

The repercussions of antimicrobial resistance are dire:

  • Treatment Challenges: Treating infections becomes increasingly difficult, including pneumonia, tuberculosis, blood poisoning, and food-borne diseases.
  • Healthcare Burden: AMR increases healthcare costs due to prolonged hospitalization and complicated recovery.
  • Strained Health Systems: AMR adds strain to healthcare systems, impacting disease control and management.
  • Risk to Vulnerable Patients: Patients undergoing surgeries and treatments like chemotherapy face higher risks of untreatable infections.
Addressing AMR in India

India has taken several measures to combat antimicrobial resistance:

  • National Action Plan on AMR: A comprehensive plan involving various stakeholders and ministries to address AMR.
  • AMR Surveillance Network: The ICMR established a surveillance and research network to monitor drug-resistant infections.
  • Research and Collaboration: Initiatives to develop new drugs and medicines through international collaboration.
  • Integrated Approach: India’s National Action Plan focuses on a One Health approach involving coordination at different levels.
Why In News

As noted in the Lancet Planetary Journal, the presence of elevated PM2.5 levels in the air can potentially serve as a conduit for the proliferation of antibiotic-resistant bacteria and genes. This underscores the critical link between air quality and the spread of antibiotic resistance, emphasizing the need for comprehensive strategies to mitigate both environmental and health risks.

MCQs about Air Pollution’s Role in Antimicrobial Resistance

  1. What is the potential link between air pollution and antimicrobial resistance (AMR)?
    A. Air pollution causes allergies and respiratory diseases.
    B. PM2.5 can carry antibiotic-resistant bacteria and genes, contributing to AMR.
    C. Air pollution only affects water quality.
    D. PM2.5 leads to increased antibiotic usage.
    Correct Answer: B. PM2.5 can carry antibiotic-resistant bacteria and genes, contributing to AMR.
    Explanation: The PM2.5, a type of particulate matter in the air, can carry antibiotic-resistant bacteria and genes, leading to the potential development of antimicrobial resistance.
  2. Which of the following best describes antimicrobial resistance (AMR)?
    A. AMR occurs when bacteria become more susceptible to medicines.
    B. AMR is a phenomenon where bacteria evolve to resist drugs, making infections harder to treat.
    C. AMR is a process that enhances the effectiveness of antibiotics.
    D. AMR is unrelated to public health risks.
    Correct Answer: B. AMR is a phenomenon where bacteria evolve to resist drugs, making infections harder to treat.
    Explanation: The antimicrobial resistance is the process where disease-causing bacteria evolve to resist drugs, making infections more challenging to treat.
  3. What is a major driver of antimicrobial resistance (AMR) highlighted in the essay?
    A. Increased access to clean water and sanitation.
    B. Proper use of antibiotics.
    C. Lack of awareness about antibiotic resistance.
    D. Reduced air pollution.
    Correct Answer: C. Lack of awareness about antibiotic resistance.
    Explanation: A lack of awareness about responsible antibiotic use is a significant driver of antimicrobial resistance.
  4. How is India addressing the issue of antimicrobial resistance (AMR)?
    A. By promoting increased antibiotic use among the population.
    B. Through the establishment of National Action Plan on AMR and surveillance networks.
    C. By discouraging international collaboration on AMR research.
    D. By focusing solely on improving healthcare facilities.
    Correct Answer: B. Through the establishment of National Action Plan on AMR and surveillance networks.
    Explanation: The India is addressing AMR by establishing the National Action Plan on AMR, creating surveillance networks, and engaging in international collaboration for research and solutions.

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